1. Antisense - National Human Genome Research Institute
Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the template for producing messenger RNA (mRNA), which directs the ...
Antisense is the non-coding DNA strand of a gene.
2. Dutch Antisense Therapeutics Symposium
The Dutch Antisense Therapeutics Symposium is a platform to strengthen the antisense oligonucleotide research in The Netherlands.
The Dutch Antisense Therapeutics Symposium is a platform to strengthen the antisense oligonucleotide research in The Netherlands
3. Antisense Oligonucleotides: An Emerging Area in Drug Discovery ...
Antisense oligonucleotides (ASOs) bind sequence specifically to the target RNA and modulate protein expression through several different mechanisms.
Antisense oligonucleotides (ASOs) bind sequence specifically to the target RNA and modulate protein expression through several different mechanisms. The ASO field is an emerging area of drug development that targets the disease source at the RNA ...
4. Delivery of Antisense RNA Therapeutics: Darter
We are a group of researchers who, thanks to COST networking tools, are boosting RNA targeting nucleic acid drugs to reach their full potential.
Delivery of AntisenseRNA Therapeutics Delivery of AntisenseRNA Therapeutics About DARTER
5. Antisense-oligonucleotides tegen neurodegeneratie - ALS Liga
4 apr 2020 · Antisense-oligonucleotides (ASO's) hebben het potentieel om RNA en eiwitexpressie te reduceren, te herstellen of te wijzigen.
See AlsoOrigin CallthemAntisense-oligonucleotides (ASO’s) hebben het potentieel om RNA en eiwitexpressie te reduceren, te herstellen of te wijzigen. Ze kunnen dan ook mikken op de ziektepathogenese door de expressie van muterende eiwitten te wijzigen.
6. Antisense Oligonucleotide Service - Creative Biogene
Creative Biogene provides comprehensive antisense oligonucleotide services, including antisense oligonucleotide synthesis, ASO in vitro screening service ...
Creative Biogene provides comprehensive antisense oligonucleotide services, including antisense oligonucleotide synthesis, ASO in vitro screening service and ASO in vivo testing service.
7. Antisense Oligonucleotide in vitro screening assays: 5 key ... - Ncardia
24 mei 2024 · Antisense oligonucleotides (ASOs) are a short, synthetic nucleic acid molecule that can bind to specific RNA sequences and can thereby modulate ...
The 5 key considerations you need to know to design physiologically relevant ASO in vitro screening assays that will give you better predictions about efficacy and safety
8. Antisense oligonucleotide therapie tegen ALS | ALS Liga België vzw
30 aug 2016 · Antisense oligonucleotiden kunnen gericht worden tegen verschillende doelwitten en zo verschillende stappen van de genexpressie inhiberen. Deze ...
Verscheidene wetenschappelijke studies hebben aangetoond dat antisense oligonucleotiden de accumulatie van het giftige RNA (C9ORF72), kunnen blokkeren en elimineren, zonder het normale RNA, geproduceerd vanuit hetzelfde gen, te beïnvloeden.
9. DCRT Dutch Center for RNA Therapeutics
... antisense oligonucleotides, small stretches of chemically modified RNA ... The N=1 Collaborative is hosting the panel session on its website. Please ...
DCRT Dutch Center for RNA Therapeutics. DCRT focusses on splice modulation for patients with unique, eligibile mutations. This is achieved with antisense oligonucleotides, small stretches of chemically modified RNA. In exon skipping, pre-mRNA splicing is modulated such that an exon is skipped.
10. Antisense oligonucleotide-mediated disruption of HTT caspase-6 ...
Antisense oligonucleotide-mediated disruption of HTT caspase-6 cleavage site ameliorates the phenotype of YAC128 Huntington disease mice ... To that end, we use ...